Reviewed, UniProtKB/Swiss-Prot Q5UQ59 (SYR_MIMIV)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	RARS
Ordered Locus Names:	MIMI_R663

Organism

Acanthamoeba polyphaga mimivirus (APMV) [Complete proteome]

Taxonomic identifier

212035 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Mimiviridae › Mimivirus

Virus host

Acanthamoeba polyphaga (Amoeba) [TaxID: 5757]

Protein attributes

Sequence length	600 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro arginine-tRNA ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 600	600	Arginyl-tRNA synthetase		PRO_0000151665
Regions
	Motif	152 – 162	11	"HIGH" region

Sequences

	Sequence		Length	Mass (Da)
	Q5UQ59-1 [UniParc]. Last modified December 7, 2004. Version 1. Checksum: 8B35DBD6794CCE0E	FASTA	600	68,994
	10 20 30 40 50 60 MQDNLIYLAN CFLNEAIKTT LQNLNKVNII DTPELYSFVK GINTDYQFNK STKLANDCNL 70 80 90 100 110 120 DKEKIVNELI TQLKSNSFFE NISSVELEQN KSVKINGKKT NTVIKQIMIT LNISKLYLSN 130 140 150 160 170 180 RINLLYKRIL SGSSIYVPNT ITKKIIVDYS SPNIAKEMHI GHLRSTIIGE SICRVLEMCG 190 200 210 220 230 240 HDVYRINHVG DWGTQFGMLI AYIKNNQIES YTISELMNIY KESRKLFESS IDFKNQSRLE 250 260 270 280 290 300 TVSLQNGNIE SITIWQKIHK ISMNSFHEIY SLLGINNLIT KGESFYQDQM TELVNSLTSD 310 320 330 340 350 360 NKITVENDMK LMFVEGISKP FILQKSDGGF TYDTSDLTAL KYRLFIEKAD HIIYVVDSSQ 370 380 390 400 410 420 QEHFSQMFQI AEKLDWIKNQ QLQHIGFGLV LGSDGSKLKT RSGETIKLQD VIDNVVSHAS 430 440 450 460 470 480 NITRELIKQK NLDWNDDDIL TISKKIAINC IKYSDLNNPR LNNYKFDINK MLNSKGNTAV 490 500 510 520 530 540 YLMYGLARCK SILRKVPNNT VLNGDIIIEN ENSRNLLLHV LKYVEVIDQT VETMCPHYLC 550 560 570 580 590 600 IYLYDLIGSL TKFYTTNRCL EYDNDNLIGY NANNLRIVNM VKIIISKIFE LIGLEEIEQL

References

[1]	"The 1.2-megabase genome sequence of Mimivirus." Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H., La Scola B., Susan M., Claverie J.-M. Science 306:1344-1350(2004) [PubMed: 15486256] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Rowbotham-Bradford.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY653733 Genomic DNA. Translation: AAV50924.1.
RefSeq	YP_143017.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3162241.
Family and domain databases
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_MIMIV

Accession

Primary (citable) accession number: Q5UQ59

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
Last sequence update:	December 7, 2004
Last modified:	November 25, 2008
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Virus (Virus annotation project)